ĐẶC ĐIỂM VÀ TÌNH HÌNH RỐI LOẠN ĐÔNG MÁU DO QUÁ LIỀU CHỐNG ĐÔNG KHÁNG VITAMIN K TẠI BỆNH VIỆN ĐA KHOA QUỐC TẾ HẢI PHÒNG - VĨNH BẢO

Abstract

Objectives: Research clinical characteristic and coagulation disorders of patients in over-anticoagulation with vitamin k antagonist (VKAs). Methods: Description and prospective study on patients in our tertiary care with VKAs drugs had an INR testing index of more than over anticoagulation in patients were check INR index with every 4 weeks at Hai Phong - Vinh Bao International General Hospital. Results: Study on 79 patients have average age is 65.65 ± 12.17 years [33:85], all most of the elderly group (73.4%). The men group (31.6%) are lower than women group (68.4%) but there is no statistical difference (p > 0.05). Patients with hemorrahage signs account for 22.8%. The INR testing index has an average value is 5.88 ± 3.0 [3.02 - 23.95]. The group of INR> 5 level (51.9%) and the group of INR ≤5 level (48.1%) have the same ratio (p> 0.05). The group of INR> 5 level is a higher risk of bleeding than the group of INR ≤5 level (p <0.001). Conclusion: All most patients in over-anticoagulation are elderly group. The men group are lower than women group but there is no statistical difference. Patients with hemorrahage signs account for 22.8%. It have no difference in rate between the group of INR> 5 level and the group of INR ≤5 level, but the group of INR> 5 level is a higher risk of bleeding than the group of INR ≤5 level, it’s statistical significance.