THE CORRELATION BETWENT LIVER DYSFUNTION AND FLARE OF SYSTEMIC LUPUS ERYTHERMATOSUS
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Abstract
Objective: Aim to prevalence of liver disease in patient systemic lupus erythermatosus (SLE) and the correlation between liver dysfunction and flare of lupus. Method: A cross sectional study was carried out on 157 patient diagnosed with SLE according criteria of SLICC 2012. The study was conducted at Department of Allergy and Clinical Immunology in Bachmai Hospital. Result: 44/157(28,0%) patient had liver disease. White blood cell in case group 5,267±4,019 G/L lower than control group 8,509±4,331 G/L (p=0,000). C4 serum case group 0,099±0,076 g/L lower than control group 0,135±0,127 g/L (p=0,038). SLEDAI case group 12,556±7,229 greater than control group 8,179±5,191 (p=0,002). Conclusion: Exacerbation of SLE induce liver diseases.
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Keywords
SLEDAI, Flare of SLE, Liver enzyme elevate.