ĐẶC ĐIỂM HOÁ MÔ MIỄN DỊCH VÀ MỘT SỐ YẾU TỐ TIÊN LƯỢNG U LYMPHO THỂ NANG

Abstract

Follicular lymphoma (FL), which is a slow progression, can delay treatment, accounts for 20% of lymphoma, so there are not many studies. Objectives: 1. To describe immunohistochemical characteristics of follicular lymphoma at Bach Mai Hospital. 2. Analysis of some prognostic factors Subjects and methods: including 29 patients diagnosed with follicular lymphoma according to the standards of the World Health Organization WHO 2008, revised in 2016 [1], [2]. Result: Maker CD23(n=8), 50% positive, 100% positive CD20, 65.5% positive CD10, total negative CD3, CD5 negative on study patient, positive BCL2 82.75%, BCL6 positive 62.06% MUM1 positive 41.37%. ECOG score of 2 or less accounts for 91.3%, high risk according to FLIPI accounts for 65%, Ki67 index < 40% has 22 patients, accounting for 75.9%, ≥40 has 7 patients, accounting for 24.1%. Conclusion: Follicular lymphoma patients are mainly positive for maker CD20, CD10, most patients have ECOG score of 2 or less, FLIPI prognostic classification is mostly high risk, and Ki67 is less than 40. primarily.