TÁC DỤNG CẢI THIỆN DÒNG TIỂU CỦA VIÊN NANG TIỀN LIỆT HV TRÊN CHUỘT CỐNG TRẮNG TĂNG SẢN LÀNH TÍNH TUYẾN TIỀN LIỆT

Abstract

Objective: Evaluating the urinary flow improvement effect of Tien liet HV capsules on model of benign prostatic hyperplasia in Wistar rats using testosterone propionate (TP). Methods: Wistar rats were injected subcutaneously with TP at a dose of 3mg/kg/24h or with sesame oil (physiological control group), and given Tien liet HV (treatment 1 and 2 groups), Dutasteride (reference group) or physiological saline (control and model groups) for 28 consecutive days. Results: Tien liet HV at dose 700mg/kg/24h and 1400mg/kg/24h reduced the number of urination times, increased volume per urination (p < 0.01 compared to the model groups). The effect of improving the urinary flow of Tien liet HV is better but not statistically significant compared with Dutasteride 5µg/kg/24h.
Conclusions: Tien liet HV capsules have the effect of improving urine flow on benign prostatic hyperplasia induced by testosterone propionate in Wistar rats.