HIỆU QUẢ ĐIỀU TRỊ LOẠN TRƯƠNG LỰC CỔ NGUYÊN PHÁT BẰNG TIÊM BOTULINUM TOXIN A TẠI BỆNH VIỆN ĐA KHOA TÂM ANH: NGHIÊN CỨU TRÊN 17 TRƯỜNG HỢP

Abstract

Objective: Evaluate the effectiveness of treatment with botulinum toxin A injection (Dysport ®) in patients with primary cervical dystonia at Tam Anh General Hospital, Hanoi. Methods: Descriptive and observational, non-interventional study on all patients with primary cervical dystonia treated with botulinum toxin A injection at Tam Anh General Hospital from November 2022 to April 2024. Results: There were 17 patients (12 men and 5 women) who met the criteria to be included in the study. Tsui score before treatment was 9.71 ± 4.34. The most commonly chosen muscles for injection are the sternocleidomastoid muscle, the stifle, and the semispinalis capitis muscle with a total injection dose of 311.76 ± 88.89 units. Time to onset of response was 10.53 ± 5.81 days. Time to maximum effectiveness is 30.06 ± 12.64 days. The effective retention time is 120.00 ± 32.86. Subjective post-injection effectiveness reached 70.00 ± 18.03%. Tsui scores 4-6 weeks after injection improved significantly compared to before treatment in all cases. Only 1 case of neck pain was recorded after injection but it was only transient. Conclusion: Botulinum toxin A injection is an effective method to treat primary cervical dystonia. Side effects are usually mild and transient.