XÁC ĐỊNH NỒNG ĐỘ KẼM, ĐỒNG HUYẾT THANH VÀ MỐI LIÊN QUAN VỚI MỨC ĐỘ HOẠT ĐỘNG CỦA BỆNH LUPUS BAN ĐỎ HỆ THỐNG

Abstract

Objectives: Determination of zinc, serum copper and clinical association of systemic lupus erythematosus. Subjects and methods: A cross sectional study uses observation to compare and contrast, including 2 groups: study group 70 patients with lupus erythematosus, 30 heathy people in the control group at National hospital of dermatology and verneology. Results: Concentration of serum zinc is lower for lupus erythematosus patients than for healthy people, p< 0,05. In each age group, serum zinc concentration in the study group was lower than in the control group. Serum zinc concentrations at 3 disease activity levels were lower than the control group with p<0.05 and the change in serum copper concentration in the study group compared to the control group was not statistically significant with p>0.05. Conclusion: There was a decrease in serum zinc levels in patients with systemic lupus erythematosus and was related to disease severity, while serum copper concentrations were unchanged compared with controls.