ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ BỆNH VẢY NẾN THỂ THÔNG THƯỜNG TRÊN BỆNH NHÂN ĐIỀU TRỊ NỘI TRÚ TẠI BỆNH VIỆN VIỆT TIỆP

Abstract

Subjects: Patients diagnosed with plaque psoriasis treated as inpatients at the dermatology department of Viet Tiep hospital from 01/2020 to 01/2023. Research methods: Cross-sectional, retrospective. Results: The research on 97 patients with plaque psoriasis recorded that the average age of the research group was 59,7; male/female ratio ~3/1. The most common comorbidity is cardiovascular disease (20.6%). The main symptoms are itching; burning pain and joint pain symptom have a low rate both. The severity of the disease before treatment was primarily severe or very severe. Damaged skin area >30% accounts for 96.9%. The average PASI before treatment was 27.4. After 2 days of treatment, skin redness symptoms improved clearly, while skin scales, lesion area and disease severity according to PASI did not change significantly. After 5 days of treatment, all symptoms improved significantly, the rate of severe disease was less than before treatment (4.1% compared to 80.4%), the average PASI decreased by 16.8 points. PASI 50 and PASI75 rates on day 5 were 62.9% and 29.9%, respectively. Treatment in the research group of patients was mainly strong corticosteroids (84.5%). Other drugs used in combination are mainly calcipotriol in 28.8% of cases. 94.8% of patients received antibiotic treatment and 99% used antihistamines. Conclusion: The treatment regimen for plaque psoriasis as recommended by the Vietnam Dermatology Association brings a high response rate, treatment effectiveness starts from day 2, and symptoms improve significantly on day 5 after treatment.